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CVE-2026-31968

HTSlib CRAM decoder vulnerable to buffer overflow

Published: Mar 18, 2026Updated: Mar 19, 2026 Sources: CVE List NVDCWE-121

Description

HTSlib is a library for reading and writing bioinformatics file formats. CRAM is a compressed format which stores DNA sequence alignment data using a variety of encodings and compression methods. For the `VARINT` and `CONST` encodings, incomplete validation of the context in which the encodings were used could result in up to eight bytes being written beyond the end of a heap allocation, or up to eight bytes being written to the location of a one byte variable on the stack, possibly causing the values to adjacent variables to change unexpectedly. Depending on the data stream this could result either in a heap buffer overflow or a stack overflow. If a user opens a file crafted to exploit this issue it could lead to the program crashing, overwriting of data structures on the heap or stack in ways not expected by the program, or changing the control flow of the program. It may be possible to use this to obtain arbitrary code execution. Versions 1.23.1, 1.22.2 and 1.21.1 include fixes for this issue. There is no workaround for this issue.

CVSS Vector Breakdown

AV:NAC:LPR:NUI:RS:UC:NI:HA:H
Exploitability
AV:NAttack Vector
Network
AC:LAttack Complexity
Low
PR:NPrivileges Required
None
UI:RUser Interaction
Required
Scope
S:UScope
Unchanged
Impact
C:NConfidentiality
None
I:HIntegrity
High
A:HAvailability
High

Weaknesses

Affected Products

Attack Graph

Products CVE Techniques Tactics

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Exploitability

Official Patch Available

MITRE ATT&CK

2 techniques
Initial Access
Privilege Escalation
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References

Timeline

Published
Mar 18, 2026
Last Updated
Mar 19, 2026

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