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CVE-2026-31967

HTSlib CRAM reader has out-of-bounds read due to improper validation of input

Published: Mar 18, 2026Updated: Mar 19, 2026 Sources: CVE List NVDCWE-125
9.1CVSSCRITICAL

Description

HTSlib is a library for reading and writing bioinformatics file formats. CRAM is a compressed format which stores DNA sequence alignment data. In the `cram_decode_slice()` function called while reading CRAM records, the value of the mate reference id field was not validated. Later use of this value, for example when converting the data to SAM format, could result in the out of bounds array reads when looking up the corresponding reference name. If the array value obtained also happened to be a valid pointer, it would be interpreted as a string and an attempt would be made to write the data as part of the SAM record. This bug may allow information about program state to be leaked. It may also cause a program crash through an attempt to access invalid memory. Versions 1.23.1, 1.22.2 and 1.21.1 include fixes for this issue. There is no workaround for this issue.

CVSS Vector Breakdown

AV:NAC:LPR:NUI:NS:UC:HI:NA:H
Exploitability
AV:NAttack Vector
Network
AC:LAttack Complexity
Low
PR:NPrivileges Required
None
UI:NUser Interaction
None
Scope
S:UScope
Unchanged
Impact
C:HConfidentiality
High
I:NIntegrity
None
A:HAvailability
High

Weaknesses

Affected Products

Attack Graph

Products CVE Techniques Tactics

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Exploitability

Official Patch Available

MITRE ATT&CK

1 technique
Collection
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References

Timeline

Published
Mar 18, 2026
Last Updated
Mar 19, 2026

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